In a modest Stratford house, in the late sixteenth century, a boy is searching for help. His twin sister, Judith, has fallen ill, and he has no idea what to do. His mother will come, carrying kind words, herbal remedies, and fear in her heart. The plague should not be here - the playhouses in London may close, but here in Stratford, far away, they are supposed to be safe. Heedlessly, the sickness has arrived from another world, crept into their home, and waits with insatiable power to shatter a family beyond recognition.